Cambridge Cell Therapy Laboratory (CCTL) is part of the Department of Clinical Haematology at Addenbrookes Hospital, and serves patients across the East of England in this busy, and progressive, HTA & JACIE accredited laboratory. Our role is to support processing and delivery of cell-based transplantation products, and cell-based medicines such as Chimaeric Antigen Receptor T cell (CAR-T) therapies; all used in the treatment of adult and paediatric haematological malignancies.
What we do at CCTL
We process over 200 apheresis products per year in both autologous and allogeneic settings, including products from donor registries from all over the World. These may be swiftly infused into patients, or cryopreserved to be thawed and infused into oncology patients after conditioning therapy, as a strategy to treat various blood-borne malignancies. Our roles as NHS based scientists make us an integral part of the clinical team and bring us directly into contact with patients as we process and deliver their cells for life-saving interventions.
Current vacancies
We are currently recruiting across various Production Scientist roles as part of a strategic expansion of our service to treat more patients across our region, with an increasing array of cellular therapies. Alongside traditional stem cell transplantation, CAR-T’ cell products now feature strongly in our latest armoury of therapies to combat cancer. These can be as licensed medicines, or as experimental therapies in clinical trials.
Our immediate plans include the development of specialist processing in transplantation products using cell and gene therapy manufacturing platforms, and we are soon to take up new state-of-art cleanrooms in the Jeffrey Cheah Building of the University of Cambridge Biomedical Campus at Addenbrookes. We intend to create a centre for translational manufacturing of novel cell and gene therapies at the heart of Cambridge University and Addenbrookes NHS Foundation Trust .
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